Chemical Forums
Specialty Chemistry Forums => Biochemistry and Chemical Biology Forum => Topic started by: jkm89 on June 11, 2009, 09:21:56 PM
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What is the difference between oxycodone and hydrocodone? I know there is an extra OH group that comes off of oxycodone, but why does this make it a stronger opiate?
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Check both terms on wikipedia
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AFAIK its largely because the -OH group is a large, polar zit on hydrocodone's face, and won't pass the BBB so easily as will oxy, as well due to being less lipophillic than the ox.
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No, the OH group is on oxycodone.