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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: Richard Jeong on January 07, 2019, 09:19:21 PM

Title: Functional Group Interconversion reference
Post by: Richard Jeong on January 07, 2019, 09:19:21 PM
Hello. I hope you reading this have a good day.
Basically, I use SciFinder to search for reactions. They are powerful if you have a scheme for exact structure.
However, it is not that helpful if I just search for functional group interconversion, since they are way too broad to search.
Are there any up-to-date references or SciFinder tips to search for functional group interchange?
Thank you, and have a good day!
Title: Re: Functional Group Interconversion reference
Post by: phth on January 15, 2019, 10:30:28 PM
Some books may provide a better source of references like Greenes protecting group compilation or a named reaction compilation. https://www.organic-chemistry.org/ is a nice website that has alot of FGI with mechanisms etc.

https://www.amazon.com/Strategic-Applications-Reactions-Organic-Synthesis/dp/0124297854/ref=pd_lpo_sbs_14_t_1/146-1628062-7147515?_encoding=UTF8&psc=1&refRID=P3WK8987G45KXJKXNV3A
https://www.amazon.com/Greenes-Protective-Groups-Organic-Synthesis/dp/0471697540/ref=sr_1_2?s=books&ie=UTF8&qid=1547609157&sr=1-2&keywords=greene%27s+protective+groups+in+organic+synthesis

Adding hydrogens on carbons tells the search engine to eliminate results that have other groups branching from them.

Try  reform the searches by transformation in the dropdown menu on the top left and it sorts the list into known transformations.

In addition, under the advances search (before entering the search) you can narrow the list to single step transformations.

Narrowing by solvents and reagents using the left sidebar helps.
Title: Re: Functional Group Interconversion reference
Post by: Babcock_Hall on January 16, 2019, 05:00:33 PM
What about Larock's book?
https://www.wiley.com/en-us/Comprehensive+Organic+Transformations%2C+A+Guide+to+Functional+Group+Preparations%2C+Two+Volume+Set%2C+2nd+Edition-p-9781118037584