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Topic: Why are these reactions catalysed by acids?  (Read 2624 times)

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Offline SumerianKing

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Why are these reactions catalysed by acids?
« on: April 07, 2012, 12:38:58 PM »
Hello, I will appreciate the help on this short answer question.

Ok so the rate of reactions of aldehydes and ketones with hydroxylamine is very sensitive to pH and is fastest in moderately acidic solutions of around pH~4.

So why are these reactions catalysed by acids??

Thank you!

Offline sjb

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Re: Why are these reactions catalysed by acids?
« Reply #1 on: April 07, 2012, 01:43:32 PM »
Hello, I will appreciate the help on this short answer question.

Ok so the rate of reactions of aldehydes and ketones with hydroxylamine is very sensitive to pH and is fastest in moderately acidic solutions of around pH~4.

So why are these reactions catalysed by acids??

Thank you!

What is the mechanism of the reaction?

Offline SumerianKing

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Re: Why are these reactions catalysed by acids?
« Reply #2 on: April 07, 2012, 02:20:29 PM »
The mechanism is Aldehydes and ketones reactiong with ammonia. Its a 2 step mechanism.
So eg: a reaction between an aldehyde and hydrazine (N2H4)

Is that enough?
Thank you.

Offline sjb

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Re: Why are these reactions catalysed by acids?
« Reply #3 on: April 07, 2012, 03:12:49 PM »
The mechanism is Aldehydes and ketones reactiong with ammonia. Its a 2 step mechanism.
So eg: a reaction between an aldehyde and hydrazine (N2H4)

Is that enough?
Thank you.

Can you draw the mechanism out?

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