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Topic: Is this grignard reagent possible?  (Read 1552 times)

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Offline missUK11

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Is this grignard reagent possible?
« on: December 02, 2012, 11:10:05 AM »
Hello All,

I just wanted to know if it was possible to use this grignard reagent in a reaction

Many thanks
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Offline discodermolide

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Re: Is this grignard reagent possible?
« Reply #1 on: December 02, 2012, 11:11:07 AM »
Yes, but probably with itself!
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Offline mhanze

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Re: Is this grignard reagent possible?
« Reply #2 on: December 02, 2012, 11:14:04 AM »
Quote from: missUK11 on December 02, 2012, 11:10:05 AM
Hello All,

I just wanted to know if it was possible to use this grignard reagent in a reaction

Many thanks

In theory, on paper, yes...in "real life" synthesis you have to try to prepare it and see will it work...maybe you shoul firstly protect OH group of carboxylic acid because it is reactive and something could happen to it in process of preparation of Grignard reagent.
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Offline Dan

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Re: Is this grignard reagent possible?
« Reply #3 on: December 02, 2012, 11:42:10 AM »
Think about what functional groups Grignard reagents react with. You cannot make a Girgnard reagent that contains these groups.
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