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Topic: NMR diastereomers  (Read 13152 times)

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Offline CHEKAL

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Re: NMR diastereomers
« Reply #15 on: January 06, 2013, 05:36:41 PM »
most lines are doublets yes, does that mean a triplet would have 6 peaks too?

Offline discodermolide

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Re: NMR diastereomers
« Reply #16 on: January 06, 2013, 05:38:28 PM »
A triplet has three peaks, in a 1:2:1 ratio.
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Offline CHEKAL

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Re: NMR diastereomers
« Reply #17 on: January 06, 2013, 05:40:11 PM »
then which peaks would appear as doublets due to coupling between the different configurations?

Offline discodermolide

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Re: NMR diastereomers
« Reply #18 on: January 06, 2013, 05:44:24 PM »
Each of the protons on the aziridine ring will appear as a doublet, integrating for 1H.
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Re: NMR diastereomers
« Reply #19 on: January 06, 2013, 05:49:50 PM »
oh i see! thanks :) does this mean the difference in hight between the two peaks would give an approximate ratio of the two configurations in the yield?

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Re: NMR diastereomers
« Reply #20 on: January 06, 2013, 05:51:12 PM »
Yes that is correct. If you measure the integrals you can estimate the proportions of each diastereoisomer.
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