[monmoshi]

Why in condition of reduction of nitrile to primary amine use MeOH saturated with ammonia gas as a solvent?

[discodermolide]

Because it prevents the formation of secondary and higher amines. Have a look at the mechanism and see if you can understand where these could be formed.

[monmoshi]

Because it prevents the formation of secondary and higher amines. Have a look at the mechanism and see if you can understand where these could be formed.

Thanks for your answer and could you show me the mechanism. I attempted to find but I did't meet it.

[orgopete]

Hint, imine.

[Arkcon]

Here's a reference with many other references on the subject:  http://www.arkat-usa.org/get-file/23388/