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Topic: ATP Synthesis  (Read 1632 times)

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Offline nicougrik

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ATP Synthesis
« on: February 11, 2016, 10:48:19 AM »
I was wondering how you would go about synthesizing Adenosine triphosphate (ATP) in the lab ? (non-Biosynthetically).
Please give your opinions, and link any previous works on the matter if you'd like.

Thank you
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Offline Babcock_Hall

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Re: ATP Synthesis
« Reply #1 on: February 11, 2016, 03:56:57 PM »
It is a forum rule that you must show your attempt before we can help you.  Fortunately, there are reasons to synthesize ATP chemically, which means that methods exist.
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Offline BRSM

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Re: ATP Synthesis
« Reply #2 on: February 13, 2016, 10:54:13 PM »
I am curious if you ask as an academic exercise, or for practical reasons. ATP is not expensive to buy---it's about $20/gram, and I can't see me (for one) making it for less that. Hell, you can buy it on amazon (http://www.amazon.com/Adenosine-5-triphosphate-disodium-salt-trihydrate-Gram/dp/B00I31ZBSO). Adenosine is even cheaper, and that 5' phosphorylation is well known. Otherwise, make a purine, make a ribose; couple; add a phosphate. This chemistry is extremely well studied. Do you want to discuss specifics?
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Offline Babcock_Hall

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Re: ATP Synthesis
« Reply #3 on: February 14, 2016, 02:36:17 PM »
One reason to make it is to add O-18 or other isotopic labels.
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