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Topic: Ph problems??  (Read 1561 times)

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Offline Frankenstein_2016

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Ph problems??
« on: July 14, 2016, 10:48:40 AM »
Converting Benzocaine>>>>>>benzocaine hydrochloride


Hi can anybody help me solve this problem??
Benzocaine>>>>>benzocaine Hydrochloride

I am doing an acid base extraction using benzocaine base
Using the following method
Dissolving benzocaine base in acetone
Also Using 36% hcl and methanol
I am getting a final ph of around 2.5
How do I raise the ph and also I think this is because the acid is getting trapped inside the crystals
Anybody help?

Offline AWK

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Re: Ph problems??
« Reply #1 on: July 14, 2016, 10:50:57 AM »
Hint - neutralization of acid. For esters in organic solvents very often K3CO3 is used.

[something gone wrong with subscripts]
« Last Edit: July 15, 2016, 02:39:09 AM by AWK »
AWK

Offline phth

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Re: Ph problems??
« Reply #2 on: July 15, 2016, 02:14:00 AM »
Are you sure that is what an extraction is called?  What you have stated is you will protonate a neautral molecule in partially solvating conditions.  An extraction involves using a system that can be partitioned.  The only thing possible is hexane, and the partition coef will still be s#*$ if you try

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