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Topic: Chloro gabalactam  (Read 1945 times)

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Offline vamsikrishna

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Chloro gabalactam
« on: February 13, 2017, 10:23:01 AM »
Can someone please kindly know the possible way of formation of chloro gaba lactam impurity in the synthesis of GABAPENTIN ASAP

Offline AWK

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Re: Chloro gabalactam
« Reply #1 on: February 13, 2017, 10:38:21 AM »
You should show your method of synthesis. My guess - you have gamapentin lactam and gamapentin hydrochloride mixture.
AWK

Offline vamsikrishna

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Re: Chloro gabalactam
« Reply #2 on: February 13, 2017, 12:18:58 PM »
Yes I do have gabapentin lactam and gabapentin hydrochloride mixture, please let me know what would be the core reaction for formation of chloro gabalactam

Offline AWK

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Re: Chloro gabalactam
« Reply #3 on: February 13, 2017, 12:54:18 PM »
Gabapentin lactam does not form hydrochloride.
AWK

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