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Author Topic: Chloro gabalactam  (Read 159 times)

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vamsikrishna

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Chloro gabalactam
« on: February 13, 2017, 04:23:01 AM »

Can someone please kindly know the possible way of formation of chloro gaba lactam impurity in the synthesis of GABAPENTIN ASAP
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AWK

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Re: Chloro gabalactam
« Reply #1 on: February 13, 2017, 04:38:21 AM »

You should show your method of synthesis. My guess - you have gamapentin lactam and gamapentin hydrochloride mixture.
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vamsikrishna

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Re: Chloro gabalactam
« Reply #2 on: February 13, 2017, 06:18:58 AM »

Yes I do have gabapentin lactam and gabapentin hydrochloride mixture, please let me know what would be the core reaction for formation of chloro gabalactam
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AWK

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Re: Chloro gabalactam
« Reply #3 on: February 13, 2017, 06:54:18 AM »

Gabapentin lactam does not form hydrochloride.
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