Chemical Forums

Please login or register.

Login with username, password and session length

Sponsored links

Pages: [1]   Go Down

Author Topic: Mosher acid NMR  (Read 1271 times)

0 Members and 1 Guest are viewing this topic.

kriggy

  • Chemist
  • Sr. Member
  • *
  • Mole Snacks: +99/-15
  • Offline Offline
  • Posts: 1179
Mosher acid NMR
« on: April 21, 2017, 03:19:37 AM »

Hi im digging through NMR determination of absolute configuration and have question about mosher´s acid method:
Lets say I have derivative with configuration X and then make the derivatives with configuration R-X and S-X. I compare the two spectra - some signals are downfield and some upfield so I can deduce the configuration. However, I never run the method until recently and found out that the derivatives compared to the parrent compound have the signals shifted the same way. Is that a common ? I mean, I thought I compare the spectra of derivatives to the spectra of parrent compound as well but then I cant get any information unless I compare ONLY derivatives. See the attached picture for more clear explanation -
 blue: non derivatized amine, green and red MTPA amides.

Pages: [1]   Go Up
 

Mitch Andre Garcia's Chemical Forums 2003-Present.

Page created in 0.169 seconds with 24 queries.