April 25, 2024, 05:37:06 AM
Forum Rules: Read This Before Posting


Topic: Equivalence salts  (Read 1883 times)

0 Members and 1 Guest are viewing this topic.

Offline minsc458

  • New Member
  • **
  • Posts: 3
  • Mole Snacks: +0/-0
Equivalence salts
« on: July 14, 2018, 07:13:02 AM »
Hello, do you know the equivalence of the differents salts of this molecule :

10 mg Tranylcypromine sulfate Molecular Weight : 364.46 g/mol
10 mg Tranylcypromine hydrochloride Molecular weight :169.65 g/mol

10 mg Tranylcypromine hydrochloride will have 2.14 times more tranylcypromine than 10 mg Tranylcypromine sulfate.
Is it correct?

Thanks for your help

Offline billnotgatez

  • Global Moderator
  • Sr. Member
  • ***
  • Posts: 4402
  • Mole Snacks: +223/-62
  • Gender: Male
Re: Equivalence salts
« Reply #1 on: July 14, 2018, 05:13:32 PM »
Can we assume the following
 considering there are many results from searching

From PubChem

Tranylcypromine sulfate
  MW: 364.460 g/mol
  MF: C18H24N2O4S
Tranylcypromine hydrochloride
  MW: 169.652 g/mol
  MF: C9H12ClN
Tranylcypromine
  MW: 133.194 g/mol
  MF: C9H11N

Offline minsc458

  • New Member
  • **
  • Posts: 3
  • Mole Snacks: +0/-0
Re: Equivalence salts
« Reply #2 on: July 14, 2018, 05:30:30 PM »
Yes it's the first two results.

the difference in molecular weight means 10 mg of the sulfate form is two times less potent than 10 mg of the hydrochloride form ?

Offline wildfyr

  • Global Moderator
  • Sr. Member
  • ***
  • Posts: 1771
  • Mole Snacks: +203/-10
Re: Equivalence salts
« Reply #3 on: July 14, 2018, 05:48:39 PM »
No, they are about the same. The sulfate has two transylamines to one sulfate, but the hydrochloride is 1 amine to each chloride. It's because sulfate is a divalent anion, and chloride is monovalent.

Offline minsc458

  • New Member
  • **
  • Posts: 3
  • Mole Snacks: +0/-0
Re: Equivalence salts
« Reply #4 on: July 14, 2018, 05:58:16 PM »
ok thanks for the explanation.

Sponsored Links