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Topic: Functional Group Interconversion reference  (Read 1529 times)

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Offline Richard Jeong

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Functional Group Interconversion reference
« on: January 07, 2019, 09:19:21 PM »
Hello. I hope you reading this have a good day.
Basically, I use SciFinder to search for reactions. They are powerful if you have a scheme for exact structure.
However, it is not that helpful if I just search for functional group interconversion, since they are way too broad to search.
Are there any up-to-date references or SciFinder tips to search for functional group interchange?
Thank you, and have a good day!
« Last Edit: January 07, 2019, 11:59:44 PM by Richard Jeong »

Offline phth

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Re: Functional Group Interconversion reference
« Reply #1 on: January 15, 2019, 10:30:28 PM »
Some books may provide a better source of references like Greenes protecting group compilation or a named reaction compilation. https://www.organic-chemistry.org/ is a nice website that has alot of FGI with mechanisms etc.

https://www.amazon.com/Strategic-Applications-Reactions-Organic-Synthesis/dp/0124297854/ref=pd_lpo_sbs_14_t_1/146-1628062-7147515?_encoding=UTF8&psc=1&refRID=P3WK8987G45KXJKXNV3A
https://www.amazon.com/Greenes-Protective-Groups-Organic-Synthesis/dp/0471697540/ref=sr_1_2?s=books&ie=UTF8&qid=1547609157&sr=1-2&keywords=greene%27s+protective+groups+in+organic+synthesis

Adding hydrogens on carbons tells the search engine to eliminate results that have other groups branching from them.

Try  reform the searches by transformation in the dropdown menu on the top left and it sorts the list into known transformations.

In addition, under the advances search (before entering the search) you can narrow the list to single step transformations.

Narrowing by solvents and reagents using the left sidebar helps.


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