Are you talking about the meso isomer? No, you don't change the stereochemistry, but you change which carbon is numbered 2! With everything else being symmetrical, the carbon with the D is numbered 2. Then you get the compounds I named, what might be alternatively called, say, (2S, 5R) 2-deutero.. and (2S, 5R) 5-deutero.... But if you put the original molecule the other way round - call it (2R, 5S) 2,5-diphenylhexane, rather than (2S, 5R)... (but you can see that these are the same molecule) you get (2R, 5S) 2-deutero... and (2R, 5S) 5-deutero... But (2S, 5R) 5-deutero.. is the same as (2R, 5S) 2-deutero... So either way you get the same pair of enantiomers.
These hydrogens in a meso compound are enantiotopic. In the RR they are homotopic. General rule.