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Chemistry Forums for Students => Analytical Chemistry Forum => Topic started by: Thet619 on October 09, 2015, 09:50:41 AM

Title: Amount of Resin Needed for Ion Exchange Chromatography
Post by: Thet619 on October 09, 2015, 09:50:41 AM

Hi,
how can I calculate the amount of resin I need (e.g. DOWEX50WX4 with a total exchange capactity of 1.1 meq/ml) if I want to convert 1mmol of NaCl into its acid?

Thanks

Title: Re: Amount of Resin Needed for Ion Exchange Chromatography
Post by: Babcock_Hall on October 09, 2015, 04:35:42 PM

Others here may have a more sophisticated approach, but I often aim for a large excess, about twentyfold, when estimating how much resin to use.  Another consideration is the relative affinities of the resin for the two ions in question.  IIRC sodium binds slightly more strongly than protons, but you should double-check this.