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Chemistry Forums for Students => High School Chemistry Forum => Topic started by: domagoj99 on July 26, 2016, 05:39:19 PM

Title: Salicylic acid impurity in old Aspirin tablets
Post by: domagoj99 on July 26, 2016, 05:39:19 PM

For a laboratory experiment at my school I wanted to test how much salicylic acid there is in old Aspirin tablets. However, I am not quite sure how to do this. I know that a titration won't work, because it only tells how much acid there is in the Aspirin solution, but does not indicate how much of the salicylic acid is present.

Can someone help me to find a method to get quantitative data?

Thank you in advance for your answer!!  :)

Title: Re: Salicylic acid impurity in old Aspirin tablets
Post by: AWK on July 26, 2016, 07:05:48 PM

The first page of GOOGLE search: determination of salicylic acid in aspirin tablets
shows you many methods.

Title: Re: Salicylic acid impurity in old Aspirin tablets
Post by: Mitch on July 28, 2016, 12:17:58 PM

Determination of Salicylic Acid in Aspirin
C. W. Strode, F. N. Stewart, H. O. Schott, O. J. Coleman
Anal. Chem., 1957, 29 (8 ), pp 1184–1186
Publication Date: August 1, 1957 (Article)
DOI: 10.1021/ac60128a022 (http://pubs.acs.org/doi/abs/10.1021/ac60128a022)

Title: Re: Salicylic acid impurity in old Aspirin tablets
Post by: domagoj99 on July 31, 2016, 04:18:13 PM

Thank you for the replies, really appreciate it! However, all of the methods were using a spectrophotometer.. seems that's the only way to do it.