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Topic: N-quaternization (Uncertain of the name of the reaction)  (Read 2760 times)

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Offline Super Newb

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N-quaternization (Uncertain of the name of the reaction)
« on: May 18, 2012, 11:59:11 AM »
I am looking at a reaction whereby R-Br (X) reacts with the N of the indoline. I have been trying to search for the mechanism of the reaction and how would people normally call this reaction. Any help will be greatly appreciated :D

Offline discodermolide

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Re: N-quaternization (Uncertain of the name of the reaction)
« Reply #1 on: May 18, 2012, 12:29:19 PM »
I am looking at a reaction whereby R-Br (X) reacts with the N of the indoline. I have been trying to search for the mechanism of the reaction and how would people normally call this reaction. Any help will be greatly appreciated :D

Is this not the Hoffmann degradation?
See http://en.wikipedia.org/wiki/Hofmann_elimination
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Offline fledarmus

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Re: N-quaternization (Uncertain of the name of the reaction)
« Reply #2 on: May 21, 2012, 08:02:31 AM »
Actually, I think you are looking for this one...

http://en.wikipedia.org/wiki/Menshutkin_reaction

Offline Dan

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Re: N-quaternization (Uncertain of the name of the reaction)
« Reply #3 on: May 21, 2012, 08:21:08 AM »
The mechanism is probably SN2.
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