[jweiss]

Hey,

I need to know how to inactivate Aflatoxin B1 and the underlying molec. mechanism for safe and clean handling of the toxin. I will use Aflatoxin B1 to generate a genome-wide mutagenesis profil in C.elegans. This webpage:

http://www.cbwinfo.com/Biological/Toxins/aflatoxins.html


suggest concentrated ammonia and sodium bisulfite for inactivation. How does that work on a molecular level? Any Ideas for other substances to inactivate it? Any help with handling and safety = waste disposal on this toxins are more than welcome!

Cheers,
Joerg

[discodermolide]

Hey,

I need to know how to inactivate Aflatoxin B1 and the underlying molec. mechanism for safe and clean handling of the toxin. I will use Aflatoxin B1 to generate a genome-wide mutagenesis profil in C.elegans. This webpage:

http://www.cbwinfo.com/Biological/Toxins/aflatoxins.html


suggest concentrated ammonia and sodium bisulfite for inactivation. How does that work on a molecular level? Any Ideas for other substances to inactivate it? Any help with handling and safety = waste disposal on this toxins are more than welcome







Cheers,
Joerg

Look in Google under aflatoxins waste disposal.
They suggest bleach.