Chemical Forums
Specialty Chemistry Forums => Biochemistry and Chemical Biology Forum => Topic started by: belven on August 02, 2014, 06:08:06 PM
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Hi. Please, could anyone tell me about what's the name and what kind of stuff is this?
O-(4-Hydroxy-3-Iodophenyl)-3-Iodo-L-Tyrosine
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Ummm ... what's the question again? You want the name, of something that you know the name of? You have other questions, but instead of asking scientific parameters, you want to know "stuff?" Where did you find it, and why do you need to know? Do you understand chemical nomenclature, and do you recognize any parts of the name?
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Hi, yes 'stuff' because I do not know what it is so I'ld like to know about its name, about if it's an aminoacid or an enzyme or a sort of hormone-like substance or what?
I saw it was named onto the label of a fitness supplement
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Very interesting. Off the top of my head, its not something I'd eat willingly. But I don't know everything. OK, so here's a tip -- when reading a chemical name, often (but not always unfortunately) the most important part of a chemical name is the last word. We tend to make that the "base" of the molecule, and add groups to it, naming them and their positions first. So starting with that info -- can you look up 'tyrosine' and find out what it is? This is how we help on these forums, we try to help people learn, we don't just dump complete answers to every question.
*EDIT*
Also look at this Google result: http://www.hmdb.ca/metabolites/HMDB05869
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Yes, Thanks for the help & sorry about the chemical knoledge lackness of mine. Yes, I'd already noticed that "tyrosine" but the point is I'ld want to know what exactly is. I get the feeling it's a very different substance than the plane tyrosine.
So I'ld like to know if it's for example the Tyrosine hydroxylase (or tyrosine 3-monooxygenase) or maybe the Tetrahydrobiopterin or other. don't know. The only thing I know is that it's something very different than tyrosine.
Also I'ld want to know about if it's something that human body owns and produces endogenously by itself.
http://www.chemicalbook.com/ChemicalProductProperty_EN_CB6930097.htm
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Hi belven, what you've got is a metabolite of thyroid hormones, diiodothyronine, also known as T2. Have a look here http://en.wikipedia.org/wiki/3,3'-Diiodothyronine and references and all the other thyroid hormones http://en.wikipedia.org/wiki/Thyroid_hormone .
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oh, thanks a hyper-bunch bro! it seems you're right! So it's simply the T2! When I had seen at that extralong O-(4-Hydroxy-3-Iodophenyl)-3-Iodo-L-Tyrosine formula I was scared about what stuff I eated. Actually I feel not so fine but finally i think to can say it's not a blame up the t2.
BTW one of the O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine synonimos is: 3,3'-Diiodo-L-thyronine
But the t2 synonim is 3,3'-Diiodo-thyronine
There's an "L" of more than the T2's one does not to have, so are you sure,sure,sure it's the same stuff? Thanks.
http://www.chemicalbook.com/ChemicalProductProperty_EN_CB6930097.htm
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The L in the name refers to the "handedness" (http://en.wikipedia.org/wiki/Chirality) of the molecule. Essentially, molecules can be like your right and left hands which are almost identical except they are mirror images of each other. The handedness of molecules is important in biology because many enzymes have a handedness as well and can only interact with one version of the molecule and not the other (e.g. if the enzyme is like a left-handed glove it will fit the left hand but not the right hand).
Most amino acids in the body have the L handedness, so O-(4-Hydroxy-3-Iodophenyl)-3-Iodo-L-Tyrosine is the correct version of T2. The mirror image, O-(4-Hydroxy-3-Iodophenyl)-3-Iodo-D-Tyrosine, would not act the same way in the body as the correct L version.
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Thanx a bunch to you too Yggdrasil! Very apprecciated and I think I get it. Very good explaination about that handed stuff and mirrors.
BTW this is more an endocrinology question but i try anyway: does anyone know about eating tyrosine supplements if it might get the possibility to get a permanent 'shotdown' (deficienct, decreasing) at the own tyrosine production?