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Topic: Hemiacetal and Acetal help  (Read 3532 times)

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Offline mkrcc12

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Hemiacetal and Acetal help
« on: December 07, 2006, 03:54:15 AM »
the problem states: Draw the hemiacetal and the acetal that can be formed from the C=O containing compound.

 I am completely drawing a blank here and I think it's real simple. Just escaping me. I attached the picture that goes w/ the problem.



Offline Dan

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Re: Hemiacetal and Acetal help
« Reply #1 on: December 07, 2006, 04:38:36 AM »
Start with the hemiacetal (in this case a hemiketal), what is the general structure of a hemiketal? You should be able to work out how to get a hemiketal from a ketone and an alcohol once you know the general structure of hemiketal.

Acetal (Ketal in this case) formation should be straightforward once you've done the hemiketal.

Hint: think about the mechanism for putting an isopropylidine protecting on a 1,2-diol.
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