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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: jmarjorie on December 10, 2005, 03:27:37 AM

Title: Conjugation: -Br + -OH ?
Post by: jmarjorie on December 10, 2005, 03:27:37 AM

I would like to know about a conjugation reaction between an organo-bromine (-Br) and an organo-hydroxy (-OH) compound;basically to form a C-C linkage :
C - Br   +   C - OH  --->  C - C  +  HOBr
Any such reaction(steps,conditions,reagents,rate,yield,etc) and any journal references for this ?
Thanks in advance.

Title: Re:Conjugation: -Br + -OH ?
Post by: Albert on December 10, 2005, 09:35:04 AM

These are the most common Williamson's Syntheses: the third one is absolutely the most useful.
Do you want also its detailed mechanism? I think you can easily work it out.