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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: Dekka on March 02, 2010, 08:20:11 AM

Title: Why elute with methanol in reverse SPE?
Post by: Dekka on March 02, 2010, 08:20:11 AM
Hey chem ppls.

I have a lab later today, and thought I understood what was going on.  On further reading I am now confused.

We are extracting capsaicin using acetonitrile, and then eluting it with methanol.  I thought that with reverse SPE the less polar solvent has higher eluent strength? Which would be the acetonitrile.

Can anyone explain where I am going wrong in my thoughts?