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Specialty Chemistry Forums => Nuclear Chemistry and Radiochemistry Forum => Topic started by: Siviscious on March 29, 2014, 08:21:37 PM

Title: Gadolinium and MRI
Post by: Siviscious on March 29, 2014, 08:21:37 PM
Why is Gadolinium so often used as a contrast agent in MRI as opposed to other paramagnetic elements or superparamagnetic compounds?
Title: Re: Gadolinium and MRI
Post by: Arkcon on March 30, 2014, 07:29:01 AM
Check out some of the information in this recent thread:

http://www.chemicalforums.com/index.php?topic=62664.msg226108#msg226108
Title: Re: Gadolinium and MRI
Post by: kriggy on May 10, 2014, 05:19:10 PM
Quote from: Siviscious on March 29, 2014, 08:21:37 PM
Why is Gadolinium so often used as a contrast agent in MRI as opposed to other paramagnetic elements or superparamagnetic compounds?
Well it has 7 unpaired electrons and the compounds are sufficiently stable.
What other compounds do you have in mind?
My advisor works on Mn2+ compounds which could be used as contrast agents, it is interesting alternative givent the fact that Gd is toxic but Im not realy sure why are those compounds not used, because im doing something different, but I think its because the complexes are not stable enough. If you want to learn more, you might want to read read
Manganese(II) Complexes as Potential Contrast Agents for MRI
by Bohuslav Drahos,Ivan Lukes and Éva Tóth
2012 Eur. J. Inorg Chem, 1975-1986
DOI: 10.1002/ejic.201101336