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Specialty Chemistry Forums => Biochemistry and Chemical Biology Forum => Topic started by: shard on September 02, 2014, 03:50:32 AM

Title: Why is the SSRI "citalopram hydrobromide" not called "citalopram hydrofluoride"?
Post by: shard on September 02, 2014, 03:50:32 AM

The formula for the drug is C₂₀H₂₁FN₂O.

Title: Re: Why is the SSRI "citalopram hydrobromide" not called "citalopram hydrofluoride"?
Post by: discodermolide on September 02, 2014, 04:16:52 AM

The fluorine is attached to an aromatic ring.
The hydrobromide means it is a salt, formed between the tertiary amine and hydrobromic acid, HBr.
This has several effects, some are; it helps to obtain a crystalline compound, it helps the aqueous solubility of the drug and it helps stabilise the molecule.