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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: orgasynth on May 09, 2006, 11:19:43 PM

Title: synthesis of 1-naphthalene sulfonic acid
Post by: orgasynth on May 09, 2006, 11:19:43 PM

dear members,
kindly suggest me the synthetic conditions for 1-naphthalene sulfonic acid
thanks

Title: Re: synthesis of 1-naphthalene sulfonic acid
Post by: AWK on May 10, 2006, 01:06:56 AM

http://www.meta-synthesis.com/webbook/24_complexity/complexity3.html

Title: Re: synthesis of 1-naphthalene sulfonic acid
Post by: Will on May 10, 2006, 07:04:09 AM

When sulfonating naphthalene, the kinetically favoured product is 1-naphtalene sulfonic acid, so you want to use a temperature lower than 100^oC (around 80^oC most websites say).

You can sulfonate with conc. H₂SO₄, but because the reaction is relatively slow it may be better to use oleum (SO₃ in H₂SO₄).

Title: Re: synthesis of 1-naphthalene sulfonic acid
Post by: saltyf on May 19, 2006, 03:48:17 AM

Tetrahedron Letters  (2004),  45(35),  6607-6609 have a detailed description of the reaction condition