Chemical Forums

Chemistry Forums for Students => Undergraduate General Chemistry Forum => Topic started by: avbennett on March 22, 2018, 10:27:23 AM

Title: pKa Enoxaparin help me!!
Post by: avbennett on March 22, 2018, 10:27:23 AM

Hello please would someone be able to help me to understand which functional groups in Enoxaparin are responsible for the 4 different pKa's? They are -2, -2, -2 and 2.9. Thanks!

Title: Re: pKa Enoxaparin help me!!
Post by: sjb on March 22, 2018, 11:00:41 AM

cf also https://www.reddit.com/r/chemistry/comments/86btew/anybody_know_the_four_functional_groups/

Title: Re: pKa Enoxaparin help me!!
Post by: wildfyr on March 22, 2018, 03:29:10 PM

The second main comment on reddit is correct.

Title: Re: pKa Enoxaparin help me!!
Post by: Babcock_Hall on March 22, 2018, 03:41:17 PM

Some of what is on the Reddit thread is misleading.  Hydrogen bond donors or acceptors are one thing; transfer of a proton from an acid to a base is something else.