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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: gabsalks on June 30, 2019, 11:43:10 PM

Title: Synthesis of ondansetron
Post by: gabsalks on June 30, 2019, 11:43:10 PM

Hi guys,

I'm having serious trouble with this homework. The first part I've already solved, it's the second one (the one marked with the "?*") that got me stuck. I'm not sure what to add to the carbonyl group that will facilitate the next reactions. Can someone give me a light?

Thanks!

Title: Re: Synthesis of ondansetron
Post by: rolnor on July 01, 2019, 04:25:09 AM

In the first step, will not the aldehyde react with the amino-group?

Title: Re: Synthesis of ondansetron
Post by: gabsalks on July 01, 2019, 10:28:24 AM

Hi rolnor, thanks for the reply.
I think the way it's written may be a little confusing. The reactions have to happen in this order.

Title: Re: Synthesis of ondansetron
Post by: Babcock_Hall on July 01, 2019, 02:39:02 PM

If you work backward from your product, something may occur to you.