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Chemistry Forums for Students => Organic Chemistry Forum => Organic Chemistry Forum for Graduate Students and Professionals => Topic started by: Bertrand on January 07, 2020, 06:28:38 AM

Title: Synthesis of N-Acyl-N,O-alcohol
Post by: Bertrand on January 07, 2020, 06:28:38 AM

 :) Hello everyone

I have some problems with making a connection in order to reach the final product of my synthesis.

I want to connect and amide an aldehyde thought a nucleophilic addition in order to get an N, O-alcohol product (Hemiaminal).

could you please give some advice? I have been trying to make that connection for a month using several papers but none of them lead me to the product.

Thank you very much in advance for your propositions

Title: Re: Synthesis of N-Acyl-N,O-alcohol
Post by: sjb on January 07, 2020, 08:46:46 AM

Please don't cross-post. Locked here