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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: JoeyBob on March 16, 2020, 08:57:36 PM

Title: Ortho-Para director question.
Post by: JoeyBob on March 16, 2020, 08:57:36 PM

If you have an activating substituent that's an ortho-para director, how do you determine if the ortho product is the major product or if the para product is the major product?

Title: Re: Ortho-Para director question.
Post by: chenbeier on March 17, 2020, 05:03:39 AM

Not easy, depend which groups already existing.

Title: Re: Ortho-Para director question.
Post by: Babcock_Hall on March 17, 2020, 11:16:06 AM

What factor or factors do you think might come into play?

Title: Re: Ortho-Para director question.
Post by: JoeyBob on March 17, 2020, 04:03:54 PM

Quote from: Babcock_Hall on March 17, 2020, 11:16:06 AM

What factor or factors do you think might come into play?

Steric hindrance? So the Para is the primary product?

Title: Re: Ortho-Para director question.
Post by: Babcock_Hall on March 18, 2020, 04:26:50 PM

I suspect that it depends on the size of the group, but yes, that was what I was thinking as well.