Chemical Forums

Specialty Chemistry Forums => Citizen Chemist => Topic started by: adwait on March 23, 2020, 07:30:50 AM

Title: About pH of the Promethazine HCL salt salution
Post by: adwait on March 23, 2020, 07:30:50 AM

I am not that much into organic chemistry or so , and if this is the right place to post but , please help .
Promethazine Hydrochloride(C17H20N2S . HCl) when dissolved as proportion of 25mg/ml . What would be the pH value. And will of that concentration safe for slow IV to humans.

Title: Re: About pH of the Promethazine HCL salt salution
Post by: chenbeier on March 23, 2020, 08:41:52 AM

pKa is 9.1, so it will be  slight acidic.  Calculate the concentration in mol/l

Calculation with formula of weak base.

http://www.druginfosys.com/drug.aspx?drugCode=623&type=1

Title: Re: About pH of the Promethazine HCL salt salution
Post by: AWK on March 23, 2020, 09:11:57 AM

IV drugs are buffered and ready to use to humans safely.