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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: monoman on May 03, 2020, 03:37:54 PM

Title: Struggling in this synthesis problem
Post by: monoman on May 03, 2020, 03:37:54 PM
Hello

I need help in this synthesis problem to form this drug (attached as target molecule).
To synthesise the drug, I have to use the precursor molecule (attached), in addition to any other molecule with four or less than four carbon atoms. I've tried many approaches but no luck so far.

Any help is appreciated! Thank you!
Title: Re: Struggling in this synthesis problem
Post by: AWK on May 03, 2020, 04:47:35 PM
Multiple post!

https://chemrxiv.org/articles/Computer-Assisted_Planning_of_Hydroxychloroquine_s_Syntheses_Commencing_from_Inexpensive_Substrates_and_Bypassing_Patented_Routes_/12026439/1