Chemical Forums

Chemistry Forums for Students => Organic Chemistry Forum => Organic Chemistry Forum for Graduate Students and Professionals => Topic started by: Zeon37 on January 22, 2021, 07:44:38 PM

Title: Oxycodone synthesis
Post by: Zeon37 on January 22, 2021, 07:44:38 PM

Hi everyone! For one of my chem assignments we have to take a compound and write out the synthesis in detail and explain verbally a breakdown of each step.
I chose one of the semi-synthetic opioids—oxycodone—. I’m really confused on what to do following hydrogenation. It’s says to wash with water and dry over sodium sulfate in vacuo. Please help me!!

Title: Re: Oxycodone synthesis
Post by: Borek on January 23, 2021, 04:06:38 AM

Quote from: Zeon37 on January 22, 2021, 07:44:38 PM

write out the synthesis in detail

I am afraid discussing practicalities of the synthesis will be against our forum rules (https://www.chemicalforums.com/index.php?topic=65859.0). No problems with discussing reaction mechanism though.

Title: Re: Oxycodone synthesis
Post by: AWK on January 23, 2021, 05:34:32 AM

You must read this publication and the relevant publications cited in it carefully.