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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: AlphaScent on March 27, 2021, 11:23:07 PM

Title: Reactions at -78C on scale
Post by: AlphaScent on March 27, 2021, 11:23:07 PM

So I have a question for the process chemists out there in industry...

If possible are reactions run at -78C avoided in possible when working in the kilo lab in 50 to 200 L reactors?

I assume so because doing larger reactions than that makes the chemistry hard to implement.

Just wondering what peoples thoughts are on this.

Cheers!

Title: Re: Reactions at -78C on scale
Post by: rolnor on March 29, 2021, 05:50:30 AM

I think you try to avoid this and probably many reaction run at -78 can be performed at -25 and this temperature can easily be accomplished with ordinary refrigiration.