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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: wuwusuxi on August 13, 2021, 03:54:36 AM

Title: Crabbe Homologation
Post by: wuwusuxi on August 13, 2021, 03:54:36 AM
Has anyone had success with this reaction?  I have a refrence below.  The material is racemic methyl-2-methylhex-5-ynoate.
Title: Re: Crabbe Homologation
Post by: rolnor on August 14, 2021, 04:56:46 AM
This is a very exotic reaction, low chance that someone here has done it. Are you going to use amine as reagent? You have to be aware that the ester in the startingmaterial can form amide.