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Chemistry Forums for Students => Analytical Chemistry Forum => Topic started by: nickgamer49 on February 28, 2022, 07:48:30 AM

Title: 6 Amino Penicillianic acid project
Post by: nickgamer49 on February 28, 2022, 07:48:30 AM

Hey! I am new to research and I am trying a project on the condensation to form
phenylpenicillin
(https://pubchem.ncbi.nlm.nih.gov/compound/6-_Benzoylamino_penicillanic-acid)
from 6-APA
(https://pubchem.ncbi.nlm.nih.gov/compound/6-Aminopenicillanic-acid#section=Crystal-Structures).

 I essentially mix 6apa dissolved in basic aqueous solution and benzoyl chloride in propanone to make the product. Because our lab doesnt have any spectroscopes and such, I acidify the solution and separate it with ethyl ethanoate. I am getting really bad yield with this process and a lot is hard to control. Does anyone have a better method or even a different topic involving the chemistry of 6APA? Thanks so much!

Title: Re: 6 Amino Penicillianic acid project
Post by: billnotgatez on February 28, 2022, 07:57:46 AM

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