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Specialty Chemistry Forums => Biochemistry and Chemical Biology Forum => Topic started by: uzi4u2 on May 28, 2007, 07:49:53 PM

Title: competitive VS uncompetitive
Post by: uzi4u2 on May 28, 2007, 07:49:53 PM

good evening people . i have a small problem :

which of the following statements are true for uncompetitive inhibition : ( More then 1 are correct)

1. The inhibitor cannot bind to the enzyme substrate complex
2. The substrate cannot bind to the enzyme-inhibitor complex
3. The Km will decrease
4. The Vmax will decrease

Sadly i forgot the defenition of Uncompetitive inhibition, does it mean that that inhibitor binds to the enzyme ?

Title: Re: competitive VS uncompetitive
Post by: Yggdrasil on May 28, 2007, 10:52:53 PM

An uncompetitive inhibitor is defined as an inhibitor that binds only to the enzyme-substrate complex.

Title: Re: competitive VS uncompetitive
Post by: uzi4u2 on May 29, 2007, 07:16:12 AM

so the correct answers then will be 2 & 4 right ?