Chemical Forums
Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: dexangeles on February 22, 2005, 09:41:56 PM
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I know that Sodium acetylide would easily react via Substitution with methyl or primary halides, but...
would sodium acetylide react with an alkenyl halide (eg. H2C=CHBR) via Substitution also? Or would it be an E reaction? I'm not sure if a carbon double bonded to another carbon would still be considered primary.
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No, substitution reactions on vinyl halides don't work. The carbon halogen bond is stronger because it involves an sp2 hybrid on carbon. Also there is a large steric component to the reaction due to the substituents at the allylic position.