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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: jamaal on January 20, 2008, 10:18:14 PM

Title: Retrosynthetic Analysis!
Post by: jamaal on January 20, 2008, 10:18:14 PM

Hey I was wondering if any of you guys had any tips on how to get better at retrosynthetic analysis problems.  Thanks!

Title: Re: Retrosynthetic Analysis!
Post by: agrobert on January 21, 2008, 02:29:02 AM

learning more synthetic steps always helps and the mastery of certain subjects including C-C bonds as the most important.  EJ Corey's Logic of Chemical Synthesis is a great book

Title: Re: Retrosynthetic Analysis!
Post by: Kryolith on January 21, 2008, 03:29:39 AM

If you have access to a library try to look for

http://www.amazon.com/Organic-Synthesis-Disconnection-Stuart-Warren/dp/0471101613

Title: Re: Retrosynthetic Analysis!
Post by: russellm72 on January 21, 2008, 07:43:07 AM

Hi,

The problem with Stuart Warrens book is that it is all based on old chemistry. The principles are Ok but the methods are a bit old and school like. I would also recommend Corey's book but it depends on what level you are at.

R.

Title: Re: Retrosynthetic Analysis!
Post by: movies on January 21, 2008, 05:54:02 PM

The Warren book is outstanding.  It may seem to use "old school" reactions but if there is a "Warren" way to make a molecule, it is probably the easiest and most reliable way to do it.  In a practical sense, I think the Warren book is best for learning retrosynthesis.