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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: portugal on April 11, 2008, 04:54:43 AM

Title: extraction solvents
Post by: portugal on April 11, 2008, 04:54:43 AM

would a good extraction solvent be for separating a racemic mixture of phenylbutnaoic acid from phenylethylamine. i already known that you would use an acid to neutralise the amine component and then you need to separate that from the butyrate so i am leaning towards a polar solvent such as ethanol becuase the butyrate will move into that allowing separation from the amine????

Title: Re: extraction solvents
Post by: Yggdrasil on April 11, 2008, 06:21:59 PM

Usually in this type of extraction, you would have your uncharged species in an organic solvent and extract your acid into aqueous base.

Title: Re: extraction solvents
Post by: ARGOS++ on April 13, 2008, 08:26:35 PM

Dear Portugal;

Quote from: portugal on April 11, 2008, 04:54:43 AM

i already known that you would use an acid to neutralise the amine component and then you need to separate that from the butyrate so i am leaning towards a polar solvent such as ethanol becuase the butyrate will move into that allowing separation from the amine????

If it would work it would still remain in the aqueous Phase, because Ethanol is “fully miscible” with Water, also in case the Water would be saturated with Salt:  "Ethanol (http://en.wikipedia.org/wiki/Ethanol)”


But there are several other Solvents, which will really do the Job.
(Ethers, “Amyl-Alcohol + Salt”, higher Ketones, etc., etc.)

Good Luck!
                    ARGOS⁺⁺