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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: LabTech on April 15, 2008, 01:21:03 PM

Title: Lypholization
Post by: LabTech on April 15, 2008, 01:21:03 PM
In the experimental section of some papers I have read, I have come across the term "lypholization."  I do not remember ever learning about that as an undergrad.  Could anybody explain to me what it is and what it is used for?
Title: Re: Lypholization
Post by: chiralic on April 15, 2008, 01:34:13 PM
Hi...

Read this on: http://en.wikipedia.org/wiki/Lypholize

Regards,

Chiralic
Title: Re: Lypholization
Post by: Shazza2008 on April 15, 2008, 03:42:33 PM
This means freeze drying. An aqueous solution is shell frozen at -196 deg C (ie liquid nitrogen temperature) and then pumped on a vacuum manifold. This slowly removes the water and usually leaves a nice dry, fluffy solid.

S