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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: sprotz on November 12, 2008, 09:23:26 AM

Title: Dibromobenzene synthesis
Post by: sprotz on November 12, 2008, 09:23:26 AM

Hello,
Can anyone please tell me the methods for the synthesis of  Dibromobenzene. It is very hard to find this data on the internet.   
Title: Re: Dibromobenzene synthesis
Post by: sjb on November 12, 2008, 09:48:09 AM
Which isomer?
Title: Re: Dibromobenzene synthesis
Post by: Two00proof on November 12, 2008, 10:33:00 AM
In addition to the "what isomer" question, what starting material are you wanting to use?
Title: Re: Dibromobenzene synthesis
Post by: sprotz on November 15, 2008, 10:58:11 AM
P-dibromobenzene, from phenol possibly.
Title: Re: Dibromobenzene synthesis
Post by: agrobert on November 15, 2008, 06:06:09 PM
From benzene, Br2 HOAc. To get bromobenzene.  Then ZnBr2 to get p-bromobenzene as the major isomer.

Or from aniline, NBS, HOAc to get p-bromoaniline.  Then diazotonization of aniline with NaNO2 and subtitution with NaBr to get p-bromobenzene.

From phenol is tricky.  Give it a shot?
Title: Re: Dibromobenzene synthesis
Post by: sprotz on November 16, 2008, 04:35:58 AM
Thanks, that information more than helped.