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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: laserni on September 25, 2009, 02:14:40 PM

Title: solvent extraction
Post by: laserni on September 25, 2009, 02:14:40 PM

I am running a reaction in neat TFA. After completion, I've neutralised excess TFA by NaOH and then extracted the aqueous layer with dichloromethane and dried over Mag sulfate. However, when I'm trying to dissolve the resulting residue in DMSO-d6 or CDCl3, it is forming a suspension rather than a clear solution. Could you please help me to fix this?

Title: Re: solvent extraction
Post by: gfunk on September 30, 2009, 04:00:41 PM

You're extracting the organic component into the DCM layer and trying to dissolve that component into DMSO-d6 or CDCl₃?