Chemical Forums
Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: wallysheng on November 19, 2009, 10:04:45 AM
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We have a project recently need to synthesize 5-(1H-Pyrazol-4-yl)thiophene-2-carboxylic Acid for about 10-20grams.
Has anybody done this compound before? Do you have any suggestion or literature for us to refer to?
Thank you!
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What about Suzukis or similar with 4-halopyrazole and 5-boronic esters of thiophene-2-carboxylic acid?
Seems that aryl bond is fundamental to making this class of molecule.
How did the difluorobicycle work out - I note it's not on your website?