Chemical Forums

Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: icecoldstar on November 23, 2009, 07:15:23 PM

Title: organic chem question about reactivity
Post by: icecoldstar on November 23, 2009, 07:15:23 PM: If i have these two compounds

(http://i2.photobucket.com/albums/y39/eatpumpkins/Untitled-155.jpg)

Which one is more reactive towards Benzaldehyde
Title: Re: organic chem question about reactivity
Post by: Schrödinger on November 23, 2009, 10:23:36 PM: What is the reaction that you want to perform?
Title: Re: organic chem question about reactivity
Post by: icecoldstar on November 23, 2009, 10:37:33 PM: its the aldol reaction and the product should be like the follwing:

(http://i2.photobucket.com/albums/y39/eatpumpkins/Untitled-156.jpg)

aka synthesis of chalcones
Title: Re: organic chem question about reactivity
Post by: jacy.cn on November 24, 2009, 03:12:02 AM: two of the start material should be react with Benzaldehyde
I think EA may be more easy
The reaction may be used base,for example Na(H,OR)?
But why you not remove methyl acetate from 1-phenyl-Ethanone?
its bp is only 57degree
Title: Re: organic chem question about reactivity
Post by: James Newby on November 24, 2009, 05:18:00 AM: Well the first step in an aldol reaction is formation of an enolate. Which has the most acidic protons next to the carbonyl?
Title: Re: organic chem question about reactivity
Post by: Schrödinger on November 24, 2009, 09:05:29 AM: Well, the product has 2 benzene rings.
Now look at the reactants.
Title: Re: organic chem question about reactivity
Post by: icecoldstar on November 25, 2009, 12:46:27 AM: Benzaldehyde has a ring on it.... so it react with the beta-carbon and all of them connect right?