Chemical Forums
Chemistry Forums for Students => Organic Chemistry Forum => Organic Chemistry Forum for Graduate Students and Professionals => Topic started by: saimark143 on September 19, 2011, 11:33:24 AM
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Hai All,
I am working in the field of natural products and as part of my work, i need to convert a primary alcohol and an aldehyde into acid group. My molecule is of phenoxazone type with the substituents of primary alcohol and aldehyde at position 9. Position 1 has -COOH group and position 3 has -NH2 group.
Can anyone help me out wrt the conversion using the extract (wherein the compounds are present).
Kindly see the attached document.
Thanking you
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A popular and mild sequence for the oxidation of alcohols to acids is oxidation to the aldehyde with Dess-Martin periodinane, and then oxidation of the aldehyde to the acid by a Pinnick oxidation.
There are many methods though, the question is quite broad. Try a literature search to narrow down your options.