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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: yxw1987 on October 18, 2011, 10:12:49 AM

Title: can guanidine hydrochloride derivatives react with isocyanate ?
Post by: yxw1987 on October 18, 2011, 10:12:49 AM

it's well known that the isocyanates can react with compounds containing active hydrogen, I want to know whether the isocyanates react with guanidine hydrochloride derivatives? ???

Title: Re: can guanidine hydrochloride derivatives react with isocyanate ?
Post by: Honclbrif on October 18, 2011, 11:11:52 AM

Yes they can

Title: Re: can guanidine hydrochloride derivatives react with isocyanate ?
Post by: sjb on October 18, 2011, 12:45:28 PM

Quote from: yxw1987 on October 18, 2011, 10:12:49 AM

it's well known that the isocyanates can react with compounds containing active hydrogen, I want to know whether the isocyanates react with guanidine hydrochloride derivatives? ???

I would imagine that the isocyanate would probably react with HCl to liberate carbon dioxide and the ammonium salt, if the reaction were not kept dry. However, if it were, then perhaps it's possible - do you have access to something like Scifinder or similar?