Chemical Forums
Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: furaniki18 on December 17, 2011, 09:41:20 AM
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what is the mechanism behind reaction between grignard reagent and amide? does it form an alkane?
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No, alkanes are not formed.
The product depends on the amide; primary and secondary amides react differently compared to tertiary amides.
What do you think would happen if you treated a primary or secondary amide with a Grignard?
For tertiary amides, the mechanism begins in an analogous fashion to the reaction of an ester with a Grignard. Hint: Weinrieb amide