Chemical Forums
Chemistry Forums for Students => Organic Chemistry Forum => Organic Chemistry Forum for Graduate Students and Professionals => Topic started by: Farker on January 24, 2012, 10:05:11 AM
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Hi, folks,
In addition to the Lipinski rule of 5, a professor of mine made a reference to the SELECT acronym in API synthesis. For the life of me, I can't find a reference to it in any of my books. It should represent some criteria of synthetic routes for large scale manufacture of API's. Given the subject, I was expecting something along the lines of, "Sterics, Electronegativity, Lone Pairs," etc., but the best guess I could find online was:
Safety
Environment
Legal
Economics
Control
Throughput
^Is this the correct SELECT acronym - something more of a big business approach? Curious if anyone else has heard of this, or if there's an alternate acronym.