Chemical Forums
Specialty Chemistry Forums => Other Sciences Question Forum => Topic started by: constant thinker on December 22, 2005, 08:31:28 PM
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People here are a collaboration of knowledge.
Would anybody happen to know what disease is caused by a lack of a second number 5 chromosome?
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Generally aneuploidy (wrong number of chromosomes) in any of the larger chromosomes is embryonic lethal - that is embryos with lacking a copy or with an extra copy of one of the chromosomes are generally aborted spontaneously, resulting in a miscarriage. Aneuploidy will generally only result in a viable fetus if it is in one of the smaller chromosomes (e.g. trisomy 21 - Down Syndrome). Viable monosomies are even more rare, although some exist (e.g. XO - Turner's syndrome). To the best of my knowledge, monosomy 5 would be embryonic lethal. However, there is a condition called cri du chat syndrome in which the affected individual is lacking a portion of one of his/her copies of chromosome 5.
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Ok thank you. I was having trouble finding a disease caused by the lack of a second number 5 chromosome which is what showed up in my given karyotype. My teacher told me to look for other disease related to deletions of parts of chromosome 5.