Chemical Forums
Chemistry Forums for Students => Undergraduate General Chemistry Forum => Problem of the Week Archive => Topic started by: Borek on November 19, 2012, 03:03:07 PM
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Trivial, but I want to check something :)
Which of these two tripeptides will be not found between products of a natural polipeptyde hydrolysis:
A:
B:
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A
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Any explanation?
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I'd say B beacuse A is a tripiptide of three standard amino acids Asn-Cys-Gly while B is synthetic AA-Cys-Gly.
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A has Cys and Gly but I dont think it has the Asn moiety. A is Glu-Cys-Gly, isn't it?
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"A" isn't a natural polypeptide, in that it doesn't follow the usual joining of the peptide bond:
NH-C(R)-CO-NH-C(R)-CO-NH-C(R)-COOH
Instead the first amino acid in "A" Glutamate is joined to the next amino acid, Cysteine through its R group unlike that in "B" which follows the normal pattern.
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GSH is quite natural but is not synthesized using peptide pathways
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"A" isn't a natural polypeptide, in that it doesn't follow the usual joining of the peptide bond:
NH-C(R)-CO-NH-C(R)-CO-NH-C(R)-COOH
Instead the first amino acid in "A" Glutamate is joined to the next amino acid, Cysteine through its R group unlike that in "B" which follows the normal pattern.
That's the answer I was looking for.