Chemical Forums
Specialty Chemistry Forums => Biochemistry and Chemical Biology Forum => Topic started by: wow on March 08, 2013, 05:21:51 PM
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Suppose an enzyme alters the ΔG‡ of a reaction from 52 kJ mol-1 to 27 kJ mol-1.
How much faster will the catalyzed reaction proceed at 300.6K as compared to the
uncatalyzed reaction? Show your work. Remember: at 300.6K, RT = 2.5 kJ mol-1.
a.
If the enzyme in (a) is exposed to a mixed inhibitor, would you expect the
rate-enhancement to change? Why or why not?
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It is a forum rule that you must show your work. Do you know what a mixed inhibitor is? Do you have a conceptual idea of what ΔG‡ is?
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yes
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OK, good, but you still need to show your attempt at these two problems. Forum rule. Do you know any equations involving ΔG‡? When you add a mixed inhibitor to an enzyme-catalyzed reaction, what do you observe?
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no i dont im sorry i forgot them
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Then open your book or notes and check them.
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delta g =-RTlnkeq
also ln k= lnQ- delta G double dagger/ RT. I just cant figure out how to setup up the formula correctly for the first part in order to plug in the numbers. i know its the arrhenius forumula but cant seem to figure out how to use the info given. can you help by suggesting a formula which i can plug in the number s ( i learn backwards usually..)